Next-Generation Sequencing
Next-Generation Sequencing (NGS) and bioinformatics play a vital role in the development of genetic medicines. These technologies are used as analytical tools in support of advanced therapeutics manufacturing (e.g., plasmid-seq and vector-seq). NGS and bioinformatics are also employed to evaluate on- and off-target gene editing at the preclinical and clinical stages. Applications of this technology continue to grow as the field of genetic medicine evolves.
Our Expertise
The unit at Franklin Biolabs processes hundreds of NGS samples every month to support discovery and translational research needs for vector manufacturing as well as biological endpoints. Our experienced team works closely with study directors, bioinformaticians, and biostatisticians to support timely, in-depth NGS data analysis for complex projects. Franklin Biolabs is at the forefront of analytical and regulatory science for advanced therapies and offers a variety of drug substance and drug product characterization options.
Engaged more than 3,000 investigators worldwide
Support the manufacture of nearly 1,000 AAV preps a year
Our Services
Sequencing
Amplicon, plasmid, vector, RNA
Extraction
DNA, RNA, vector
Custom design
Assays, primers
